教授办公室地址

东西医学研究生院(国际经营大学馆) 228号

教授办公室电话

031) 201-2184

E-MAIL

kangch@khu.ac.kr

研究室名称

抗老化材料研究室
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研究室名称

抗老化材料研究室

研究领域

开发老化标志及发掘抗老化材料

研究室特点

1) 开发观察老化过程特殊生化现象的化学探针以及利用该物质赛选抗老化材料

2) 正在与首尔大学/高丽大学/亚洲大学等化学探针开发组进行共同研究

3) 与宾夕法尼亚州立大学(美国)退行性脑疾病研究小组进行交流与合作研究

目前研究主题

1) 开发细胞小器官氧化性损伤探针

2) 内质网(endoplasmic reticulum) 压力探针研究

3) 开发癌症特殊抗癌物质传达体

4) 开发利用内镜早期发现癌症的探针

5) 发掘细胞老化相关生化指标

今后老化相关研究主题

1) 开发细胞老化探针

2) 利用老化特殊探针,发掘赛选抗老化材料

3) 发掘皮肤抗老化材料

研究业绩

  • Glycyrrhetinic acid as a hepatocyte targeting unit for an anticancer drug delivery system with enhanced cell type selectivity.(2018 Oct 16)
  • Modulating the GSH/Trx selectivity of a fluorogenic disulfide-based thiol sensor to reveal diminished GSH levels under ER stress.(2018 Aug 7)
  • A Fluorescent Probe for Stimulated Emission Depletion Super-Resolution Imaging of Vicinal-Dithiol-Proteins on Mitochondrial Membrane.(2018 Apr 18)
  • Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores.(2018 Apr 3)
  • Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics.(2018 Jan 2)
  • Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics.(2018 Jan 2)
  • Rational Design of in Vivo Tau Tangle-Selective Near-Infrared Fluorophores: Expanding the BODIPY Universe.(2017 Sep 27)
  • Visualization of vesicular transport from the endoplasmic reticulum to lysosome using an amidine derived two-photon probe.(2017 Jun 1)
  • An endoplasmic reticulum-selective ratiometric fluorescent probe for imaging a copper pool.(2017 Apr 18)
  • Targeted tumor detection: guidelines for developing biotinylated diagnostics.(2017 Feb 9)
  • Flavin-mediated photo-oxidation for the detection of mitochondrial flavins.(2016 Nov 10)
  • Indomethacin-guided cancer selective prodrug conjugate activated by histone deacetylase and tumour-associated protease.(2016 Aug 2)
  • A carboxylesterase-selective ratiometric fluorescent two-photon probe and its application to hepatocytes and liver tissues.(2016 Jun 1)
  • A far-red, photo- and bio-stable fluorescent marker selective to the endoplasmic reticulum and its application to tunicamycin-treated HeLa cells.(2016 Jun 4)