教授办公室地址

东西医学学院(国际经营大学馆)208号

教授办公室电话

031) 201-2184

E-MAIL

kangch@khu.ac.kr

研究室名称

老人药理学 (Gerontologic Pharmacology)
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研究室名称

抗老化材料研究室

研究领域

开发老化标志及发掘抗老化材料

实验室特点

1) 开发观察老化过程特殊生化现象的化学探针以及利用该物质赛选抗老化材料

2) 正在与首尔大学/高丽大学/亚洲大学等化学探针开发组进行共同研究

3) 与宾夕法尼亚州立大学(美国)退行性脑疾病研究小组进行交流与合作研究

目前研究主题

1) 开发细胞小器官氧化性损伤探针

2) 内质网(endoplasmic reticulum) 压力探针研究

3) 开发癌症特殊抗癌物质传达体

4) 开发利用内镜早期发现癌症的探针

5) 发掘细胞老化相关生化指标

今后老化相关研究主题

1) 开发细胞老化探针

2) 利用老化特殊探针,发掘赛选抗老化材料

3) 发掘皮肤抗老化材料

研究业绩

  • Scutellarin Ameliorates Learning and Memory deficit via suppressing Amyloid formation and microglial activation in rats with chronic cerebral hypoperfusion(2018.08.27)
  • Radix Polygalae Extract Attenuates PTSD-like Symptoms in a Mouse Model of Single Prolonged Stress and Conditioned Fear Possibly by Reversing BAG1.(2018.06.30)
  • Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats.(2018.06.30)
  • Age-related decrease in stress responsiveness and proactive coping in male mice(2018.05.07)
  • Woohwangcheongsimwon Prevents High-Fat Diet-Induced Memory Deficits and Induces SIRT1 in Mice(2018.01.15)
  • Up-regulation of UVRAG by HDAC1 Inhibition Attenuates 5FU-induced Cell Death in HCT116 Colorectal Cancer Cells.(2018.01.10)
  • p-Coumaric acid enhances long-term potentiation and recovers scopolamine-induced learning and memory impairments.(2017.10.21)
  • Rational Design of In Vivo Tau Tangle-Selective Near Infrared Fluorophores: Expanding the BODIPY Universe.(2017.09.15)
  • Reduced consolidation, reinstatement and renewal of conditioned fear memory by repetitive treatment of Radix polygalae in mice(2017.05.31)
  • Loganin enhances long-term potentiation and recovers scopolamine-induced learning and memory impairments(2017.05.15)
  • Ginsenoside Rg3 improves recovery from spinal cord injury in rats via suppression of neuronal apoptosis, pro-inflammatory mediators, and microglial activation(2017.01.12)
  • Nobiletin improves emotional and novelty recognition memory but not spatial referential memory(2017.01.09)
  • Prolonged stimulation with low-intensity ultrasound induces delayed increases in spontaneous hippocampal culture spiking activity(2016.07.28)
  • Long-term Treatment with Oriental Medicinal Herb Artemisia princeps Alters Neuroplasticity in a Rat Model of Ovarian Hormone Deficiency(2015.05.15)
  • Preclinical evidence of rapid-onset antidepressant-like effect in Radix Polygalae extract(2014.02.10)